Integration of Metabolomics and 16S Ribosomal RNA Sequencing to Elucidate the Pathogenesis of Ankylosing Spondylitis

Integration of Metabolomics and 16S Ribosomal RNA Sequencing to Elucidate the Pathogenesis of Ankylosing Spondylitis

ABSTRACT Objective Despite growing interest in the gut microbiota and blood metabolome in patients with ankylosing spondylitis (AS), its role remains poorly understood. Here, we investigate how microbial and metabolic alterations contribute to AS. Methods Fecal microbiome data from 40 AS patients we...

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Main Authors: Xin Wang, Haojie Xu, Yuyan Chao, Chao Sun, Tingting Wang, Xiaoyun Fan, Lin Tang, Shengqian Xu, Changhao Xie
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Immunity, Inflammation and Disease
Subjects:
16S rRNA sequencing
ankylosing spondylitis
blood metabolome
gut microbiota
metabolomics
Online Access:https://doi.org/10.1002/iid3.70183
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https://doi.org/10.1002/iid3.70183

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