Dysfunctional mesocorticolimbic circuitry in cluster headache

Dysfunctional mesocorticolimbic circuitry in cluster headache

Abstract Background This study aimed to identify mesocorticolimbic functional abnormalities in cluster headache (CH) patients, disentangling the roles of chronification and affective symptoms. Methods Using the monetary incentive delay fMRI task to directly engage these pathways, we investigated fun...

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Main Authors: Stefania Ferraro, Greta Demichelis, Jean Paul Medina Carrion, Dan Liu, Benjamin Becker, Michael Maes, Davide Fedeli, Giuseppe Ciullo, Susanna Usai, Marina Grisoli, Luisa Chiapparini, Alberto Cecchini Proietti, Luca Giani, Anna Nigri, Massimo Leone
Format: Article
Language:English
Published: BMC 2025-05-01
Series:The Journal of Headache and Pain
Subjects:
Chronic cluster headache
Episodic cluster headache
fMRI
Monetary incentive delay task
Mesocorticolimbic system
Ventral tegmental area
Online Access:https://doi.org/10.1186/s10194-025-02017-z
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https://doi.org/10.1186/s10194-025-02017-z

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