Comprehensive transcriptomic analysis identifies cholesterol transport pathway as a therapeutic target of porcine epidemic diarrhea coronavirus

Comprehensive transcriptomic analysis identifies cholesterol transport pathway as a therapeutic target of porcine epidemic diarrhea coronavirus

Porcine epidemic diarrhea virus (PEDV) is a highly contagious virus that poses a serious threat to the global pig industry. Despite extensive efforts, the mechanism underlying virus entry for PEDV remains elusive. In this study, we first identified PEDV-susceptible and non-susceptible cell lines by...

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Bibliographic Details
Main Authors: Lilei Lv, Huaye Luo, Min Zhang, Chuntao Wu, Yifeng Jiang, Wu Tong, Guoxin Li, Yanjun Zhou, Yanhua Li, Zhao Wang, Changlong Liu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Virus Research
Subjects:
PEDV
Coronavirus
Cholesterol transport
Viral entry
Ezetimibe
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170224001953
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