Targeting Exosomal PD-L1 as a New Frontier in Cancer Immunotherapy

Targeting Exosomal PD-L1 as a New Frontier in Cancer Immunotherapy

This manuscript assesses the critical role of exosomal PD-L1 (ExoPD-L1) in immune suppression, tumor progression, and resistance to therapy. ExoPD-L1 has been identified as a key mediator of tumor immune evasion, contributing to systemic immunosuppression beyond the tumor microenvironment (TME) due...

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Bibliographic Details
Main Authors: Laura Denisa Dragu, Mihaela Chivu-Economescu, Ioana Madalina Pitica, Lilia Matei, Coralia Bleotu, Carmen Cristina Diaconu, Laura Georgiana Necula
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Current Issues in Molecular Biology
Subjects:
ExoPD-L1
exosome
immune evasion
cancer immunotherapy
therapy resistance
Online Access:https://www.mdpi.com/1467-3045/47/7/525
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