Pharmacokinetics of cannabidiol, (-)-trans-Δ9-tetrahydrocannabinol, and their oxidative metabolites after intravenous and oral administration of a cannabidiol-dominant full-spectrum hemp product to beagle dogs

Pharmacokinetics of cannabidiol, (-)-trans-Δ9-tetrahydrocannabinol, and their oxidative metabolites after intravenous and oral administration of a cannabidiol-dominant full-spectrum hemp product to beagle dogs

IntroductionThis study investigated the pharmacokinetics, safety, and tolerability of a full-spectrum CBD-dominant oil formulated in medium-chain triglycerides (MCT oil) after a single intravenous (IV) administration, a single oral (PO) administration, and multiple oral administrations of CBD at a d...

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Bibliographic Details
Main Authors: Susanna E. Kitts-Morgan, Richard A. Sams, William W. Muir
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Veterinary Science
Subjects:
dog
cannabidiol
pharmacokinetics
adverse effects
oral dosing
intravenous dosing
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1556975/full
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https://www.frontiersin.org/articles/10.3389/fvets.2025.1556975/full

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