Porcine β-Defensin 2 Expressed in <i>Pichia pastoris</i> Alleviates Enterotoxigenic <i>Escherichia coli</i>-Induced Intestinal Injury and Inflammatory Response in Mice

Porcine β-Defensin 2 Expressed in <i>Pichia pastoris</i> Alleviates Enterotoxigenic <i>Escherichia coli</i>-Induced Intestinal Injury and Inflammatory Response in Mice

Enterotoxigenic <i>Escherichia coli</i> (ETEC), a common intestinal pathogen, can colonize the intestines and induce diarrhea in piglets, which brings great economic losses to the swine industry. Antibiotics are recommended to the treatment for diarrhea caused by ETEC in weaned piglets....

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Bibliographic Details
Main Authors: Shuaiyang Wang, Huaixia Li, Yaxue Huang, Wenxiao Zhuo, Tingting Li, Tingting Jiang, Qi Huang, Rui Zhou
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Animals
Subjects:
porcine β-defensin 2
<i>Pichia pastoris</i>
enterotoxigenic <i>Escherichia coli</i>
antimicrobial activity
mouse infection model
intestinal morphology
Online Access:https://www.mdpi.com/2076-2615/15/10/1389
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