SPICE1 promotes osteosarcoma growth by enhancing the deubiquitination of FASN mediated by USP10
Abstract Background Osteosarcoma (OS) is recognized as a prevalent primary bone malignancy, particularly affecting adolescents during their growth spurts. Despite its clinical significance, the underlying biological characteristics and associated prognostic factors remain incompletely understood. Th...
Saved in:
| Main Authors: | Weilai Tong, Xinsheng Xie, Zhiguo Shu, Jiangbo Nie, Xianhe Yang, Feng Yang, Zhili Liu, Jiaming Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-02-01
|
| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-025-06248-1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
USP8 protects rat-derived H9C2 cardiomyocytes from doxorubicin-triggered ferroptosis and cell death through deubiquitination-mediated stabilization of MDM4
by: Yixi Li, et al.
Published: (2025-08-01) -
YY1 induced USP13 transcriptional activation drives the malignant progression of hepatocellular carcinoma by deubiquitinating WWP1
by: Qingwei Zhu, et al.
Published: (2025-05-01) -
Deubiquitination of DNM1L by USP3 triggers the development and metastasis of gallbladder carcinoma
by: Ruopeng Liang, et al.
Published: (2025-04-01) -
USP14 promotes osteoarthritis progression by deubiquitinating FZD8 to activate the Wnt/β-catenin signaling pathway
by: Xiaochao Chen, et al.
Published: (2025-05-01) -
The Role and Mechanism of Deubiquitinase USP7 in Tumor-Associated Inflammation
by: Luhong Wang, et al.
Published: (2024-11-01)