Establishment of an alternative splicing prognostic risk model and identification of FN1 as a potential biomarker in glioblastoma multiforme

Establishment of an alternative splicing prognostic risk model and identification of FN1 as a potential biomarker in glioblastoma multiforme

Abstract Aberrant alternative splicing and abnormal alternative splicing events (ASEs) in glioblastoma multiforme (GBM) remain largely elusive. The prognostic-associated ASEs in GBM were identified and summarized into 123 genes using GBM and LGG datasets from ASCancer Atlas and TCGA. The eleven gene...

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Bibliographic Details
Main Authors: Xi Liu, Jinming Song, Zhiming Zhou, Yuting He, Shaochun Wu, Jin Yang, Zhonglu Ren
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Glioblastoma
Alternative splicing
ASRS prognostic model
FN1
Online Access:https://doi.org/10.1038/s41598-025-91038-4
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https://doi.org/10.1038/s41598-025-91038-4

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