Differences in Mpox and Vaccinia Immunity Induced by Non-Replicating and Replicating Vaccinia-Based Vaccines

Differences in Mpox and Vaccinia Immunity Induced by Non-Replicating and Replicating Vaccinia-Based Vaccines

<b>Background</b>: The recent global outbreak with clade IIb and the concurrent emergence of clade I mpox virus in Africa show that mpox is a challenging problem. MVA-BN induces low-level mpox-neutralizing antibody responses that wane rapidly. This study was conducted to compare the mpox...

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Bibliographic Details
Main Authors: Getahun Abate, Krystal Meza, Yinyi Yu, Chase Colbert, Anna Jaunarajs, Azra Blazevic, Daniel F. Hoft, Sharon E. Frey
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Vaccines
Subjects:
mpox
vaccinia
MVA-BN
Dryvax
replication-competent
immunity
Online Access:https://www.mdpi.com/2076-393X/13/5/520
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