SDF-1/CXCR4 Axis Promotes MSCs to Repair Liver Injury Partially through Trans-Differentiation and Fusion with Hepatocytes

MSCs have become a popular target for developing end-stage liver therapies. In this study, two models of bone marrow chimeric mice were used to construct the liver failure models. Then it was found that MSCs can transdifferentiate into hepatocyte-like cells and these hepatocyte-like cells can signif...

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Bibliographic Details
Main Authors: Ning-Bo Hao, Chang-Zhu Li, Mu-Han Lü, Bo Tang, Su-Min Wang, Yu-Yun Wu, Guang-Ping Liang, Shi-Ming Yang
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2015/960387
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