A novel mitochondrial quality regulation gene signature for anticipating prognosis, TME, and therapeutic response in LUAD by multi-omics analysis and experimental verification

Abstract Background Lung adenocarcinoma (LUAD) is the predominant form of non-small cell lung cancer (NSCLC). Mitochondrial quality-related genes (MQRGs) contribute to the genesis and advancement of tumors. Despite advances in LUAD treatment and detection, early diagnostic biomarkers are still lacki...

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Bibliographic Details
Main Authors: Lijun Zeng, Sixuan Wu, Zhimin Li, Yuanbin Tang, Yeru Tan, Renji Liang, Yuehua Li
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cancer Cell International
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Online Access:https://doi.org/10.1186/s12935-025-03764-4
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