A comprehensive step-by-step approach for the implementation of target trial emulation: Evaluating fluid resuscitation strategies in post-laparoscopic septic shock as an example

A comprehensive step-by-step approach for the implementation of target trial emulation: Evaluating fluid resuscitation strategies in post-laparoscopic septic shock as an example

Objective: To develop and demonstrate a comprehensive methodological framework for target trial emulation (TTE) implementation via post-laparoscopic septic shock fluid management as a clinical case study. Methods: We designed a simulated study of 10,000 patients in which colloid resuscitation was co...

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Bibliographic Details
Main Authors: Jie Yang, Lihui Wang, Lin Chen, Pengmin Zhou, Suibi Yang, Hongjie Shen, Lifeng Xing, Pengpeng Chen, Yuetian Yu, Hongying Ni, Zhongheng Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Laparoscopic, Endoscopic and Robotic Surgery
Subjects:
Laparoscopic surgery
Sepsis
Target trial emulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2468900925000015
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