Bisacurone ameliorates myocardial ischemia/reperfusion injury in rats: regulation of inflammatory and apoptosis pathways via CHOP/GRP78 proteins

Bisacurone ameliorates myocardial ischemia/reperfusion injury in rats: regulation of inflammatory and apoptosis pathways via CHOP/GRP78 proteins

Abstract Background Myocardial infarction is caused by persistent ischemia with or without reperfusion. Bisacurone, a terpenoid present in turmeric, possesses cardioprotective properties that alleviate heart hypertrophy and diabetic cardiomyopathy. However, its effect on myocardial ischemia-reperfus...

Full description

Saved in:
Bibliographic Details
Main Authors: Xueyan Liao, Qi Wang, Xiaoming Yang, Yuan Yao, Dezhi Zhu, Jing Feng, Kechun Wang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Pharmacology and Toxicology
Subjects:
Apoptosis
Bisacurone
CHOP
cTn-I
Curcuma longa
GRP78
Online Access:https://doi.org/10.1186/s40360-025-00949-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s40360-025-00949-5

Similar Items