Enhanced anti-cancer effect of AMTB hydrochloride via chitosan nanoparticles in pancreatic cancer

Abstract Pancreatic cancer is a malignancy with poor prognosis and high mortality. This study investigated the use of chitosan nanoparticles (CS-NPs) to encapsulate AMTB, a TRPM8 inhibitor, as a novel strategy to enhance therapeutic efficacy in pancreatic cancer. TRPM8 was overexpressed in pancreati...

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Bibliographic Details
Main Authors: Jiefeng Liu, Yujing Gong, Xinyu Zeng, Miao He, Bin He, Wenbin Gao, Yong Gao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-025-14356-w
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