Non-linear microglial, inflammatory and oligodendrocyte dynamics across stages of Alzheimer's disease

Non-linear microglial, inflammatory and oligodendrocyte dynamics across stages of Alzheimer's disease

Alzheimer's disease (AD) is characterized by cognitive decline and neuropathological hallmarks including Aβ plaques and Tau tangles. Emerging evidence indicates oligodendrocyte (OL) dysfunction and demyelination also contribute to disease progression. Here, we analyzed OL markers and inflammato...

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Bibliographic Details
Main Authors: Aurélien M. Badina, Kelly Ceyzériat, Quentin Amossé, Alexandre Tresh, Laurene Abjean, Léa Guénat, Emilie Vauthey, Stergios Tsartsalis, Philippe Millet, Benjamin B. Tournier
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Neuroinflammation
Peripheral immune infiltration
Microglia
Oligodendrocytes
Myelination
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996125001664
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http://www.sciencedirect.com/science/article/pii/S0969996125001664

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