Matricellular Protein SMOC2 Potentiates BMP9-Induced Osteogenic Differentiation in Mesenchymal Stem Cells through the Enhancement of FAK/PI3K/AKT Signaling

Matricellular Protein SMOC2 Potentiates BMP9-Induced Osteogenic Differentiation in Mesenchymal Stem Cells through the Enhancement of FAK/PI3K/AKT Signaling

Mesenchymal stem cells (MSCs) can self-renew and differentiate into multiple lineages, making MSC transplantation a promising option for bone regeneration. Both matricellular proteins and growth factors play an important role in regulating stem cell fate. In this study, we investigated the effects o...

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Main Authors: Wen-Ge He, Yi-Xuan Deng, Kai-Xin Ke, Xuan-Lin Cao, Si-Yuan Liu, Yuan-Yuan Yang, Hong-Hong Luo, Xin-Tong Yao, Xiang Gao, Yu Du, Bai-cheng He, Liang Chen
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2023/5915988
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http://dx.doi.org/10.1155/2023/5915988

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