Maximizing activity and selectivity of antibody-mediated effector functions using antibody mixtures

Fc-mediated effector functions are key for conferring potent antibody-mediated killing of cancer cells. However, it is difficult to achieve highly selective targeting of cancer cells while minimizing toxicity on healthy tissue because of the expression of most receptors, albeit at lower levels, on n...

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Bibliographic Details
Main Authors: Tiexin Wang, Alec A. Desai, Greg M. Thurber, Peter M. Tessier
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:mAbs
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2025.2480666
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