Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90‐HIF‐1α‐Mediated Glycolysis in Kidney Fibrosis

Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90‐HIF‐1α‐Mediated Glycolysis in Kidney Fibrosis

Abstract Although significant progress in identifying molecular mediators of fibrosis is made, there is still controversy regarding the role and mechanism of autophagy in kidney fibrosis. Here, this study finds that autophagy related 5 (ATG5) is obviously increased in uric acid (UA), aristolochic ac...

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Bibliographic Details
Main Authors: Yan Hu, Jinqing Li, Hui Chen, Yingfeng Shi, Xiaoyan Ma, Yi Wang, Xialin Li, Qin Zhong, Yishu Wang, Daofang Jiang, Shougang Zhuang, Na Liu
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
autophagy related 5
glycolysis
heat shock protein 90
hypoxia‐inducible factor 1alpha
kidney fibrosis
Online Access:https://doi.org/10.1002/advs.202414673
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https://doi.org/10.1002/advs.202414673

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