Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis

Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis

Abstract Background Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in neuroplasticity and cognitive function, with its dysregulation linked to neurodegenerative and psychiatric disorders. Probiotics, through the gut-brain axis, may modulate BDNF levels, but evidence remains...

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Bibliographic Details
Main Authors: Reza Hashemi, Mohammad M. Hussein M. Raouf, Tanya S. Salih, Marzieh Feyzpour, Maryam Eskandarioun, Najmeh Nezamabadipour, Hossein Gandomkar
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Nutrition
Subjects:
Probiotic
Brain-derived neurotrophic factor
Gut-brain axis
Meta-analysis
Online Access:https://doi.org/10.1186/s40795-025-01152-9
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https://doi.org/10.1186/s40795-025-01152-9

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