Metagenomic next generation sequencing of plasma RNA for diagnosis of unexplained, acute febrile illness in Uganda.

Metagenomic next generation sequencing of plasma RNA for diagnosis of unexplained, acute febrile illness in Uganda.

Metagenomic next generation metagenomic sequencing (mNGS) has proven to be a useful tool in the diagnosis and identification of novel human pathogens and pathogens not identified on routine clinical microbiologic tests. In this study, we applied mNGS to characterize plasma RNA isolated from 42 study...

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Main Authors: Abraham J Kandathil, Paul W Blair, Jennifer Lu, Raghavendran Anantharam, Kenneth Kobba, Matthew L Robinson, Sultanah Alharthi, Edgar C Ndawula, J Stephen Dumler, Francis Kakooza, Mohammed Lamorde, David L Thomas, Steven L Salzberg, Yukari C Manabe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0012451
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https://doi.org/10.1371/journal.pntd.0012451

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