Gut Akkermansia enhances liver protection and facilitates copper removal during D-penicillamine treatment in a Wilson’s disease model

Gut Akkermansia enhances liver protection and facilitates copper removal during D-penicillamine treatment in a Wilson’s disease model

ABSTRACT Patients afflicted with Wilson’s disease (WD) may encounter hepatic and extraneous manifestations due to the progressive accumulation of copper in the liver and other subsequent organs. Copper-chelating agents, such as D-penicillamine (DPA), are commonly utilized in the medical treatment of...

Full description

Saved in:
Bibliographic Details
Main Authors: Xi Huang, Yanqi Jin, Tianyuan Wang, Danting Fu, Jindi Ma, Xiaopeng Yu, Yingfeng Lu, Jingyuan Song, Yu Chen, Ren Yan, Yimin Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:Microbiology Spectrum
Subjects:
copper toxicity
liver injury
gut microbiota
pharmacomicrobiomics
Akkermansia muciniphila
copper removing
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00573-24
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://journals.asm.org/doi/10.1128/spectrum.00573-24

Similar Items