The Role of Beta-Hydroxybutyrate in Mitigating the Inflammatory and Metabolic Consequences of Uric Acid

The Role of Beta-Hydroxybutyrate in Mitigating the Inflammatory and Metabolic Consequences of Uric Acid

<b>Background:</b> Uric acid (UA), a metabolite of purine and fructose metabolism, is linked to inflammation and metabolic disorders, including gout and cardiovascular disease. Its pro-inflammatory effects are largely driven by the activation of the nucleotide-binding oligomerization dom...

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Main Authors: Nicole P. Remund, John G. Larsen, Marley J. Shin, Cali E. Warren, Isabelle L. Palmer, Iris J. Kim, Elijah T. Cooper-Leavitt, Derek M. Clarke, Colson G. Beus, Richard J. Johnson, Juan A. Arroyo, Paul R. Reynolds, Benjamin T. Bikman
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Metabolites
Subjects:
uric acid
inflammation
ketones
insulin resistance
mitochondria
Online Access:https://www.mdpi.com/2218-1989/14/12/679
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https://www.mdpi.com/2218-1989/14/12/679

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