The role of TRAF2 in pan-cancer revealed by integrating informatics and experimental validation

BackgroundTumor necrosis factor (TNF) receptor associated factor-2 (TRAF2) is an E3 ubiquitin ligase and scaffolding protein that contribute to the progression of various malignant tumors. However, the role of TRAF2 expression in epigenetic, cancer prognosis, and immune responses in tumor microenvir...

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Bibliographic Details
Main Authors: Xizheng Wang, Jianfeng Yuan, Chenchen Zhang, Lingyu Kong, Enzhen Wu, Jianxin Guo, Zhongbing Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1563435/full
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