Escherichia coli Nissle 1917 efficiently expresses the RBD domain of SARS-CoV-2 spike protein without codon optimization

Abstract Bacterial outer membrane vesicles (OMVs) represent a promising and versatile platform for vaccine delivery. Their inherent self-adjuvant properties and the ability to be adorned with a wide range of heterogeneous antigens position them as a powerful tool in the fight against infectious dise...

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Bibliographic Details
Main Authors: Shanmugaraja Meenakshi, R. Suvetha, S. Ramadevi
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-99902-z
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