Cell-free hemoglobin is associated with microcirculatory perfusion disturbances and acute kidney injury in rats on extracorporeal membrane oxygenation

Cell-free hemoglobin is associated with microcirculatory perfusion disturbances and acute kidney injury in rats on extracorporeal membrane oxygenation

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving treatment, but carries a high risk of complications such as acute kidney injury (AKI). A contributor to AKI is hemolysis, which induces vasoconstriction and renal tubular cytotoxicity. Here, we have investigated a novel...

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Main Authors: Carolien Volleman, Dionne P. C. Dubelaar, Philippa G. Phelp, Roselique Ibelings, Anita M. Tuip-de Boer, Chantal A. Polet, Walter M. van den Bergh, Alexander P. J. Vlaar, Charissa E. van den Brom
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Anesthesiology
Subjects:
ECMO
Extracorporeal membrane oxygenation
Extracorporeal circulation
Endothelium
Edema
Hemolysis
Online Access:https://doi.org/10.1186/s12871-025-03251-3
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https://doi.org/10.1186/s12871-025-03251-3

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