ZIP4 promotes glycolysis in cholangiocarcinoma cells by enhancing H3K4me3 modification and activating MYCN transcription

ZIP4 promotes glycolysis in cholangiocarcinoma cells by enhancing H3K4me3 modification and activating MYCN transcription

ObjectiveTo explore the mechanism by which zinc-regulated transporters, iron-regulated transporter-likeprotein 4 (ZIP4) regulates glycolysis and its impact on tumor progression in cholangiocarcinoma (CCA), providing a theoretical basis for targeted therapy of CCA. MethodsZIP4 expression in CCA was a...

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Bibliographic Details
Main Authors: Jiwen WANG, Cheng ZHANG, Dexiang ZHANG, Xiaoling NI, Kun FAN, Houbao LIU
Format: Article
Language:English
Published: Shanghai Chinese Clinical Medicine Press Co., Ltd. 2025-06-01
Series:Zhongguo Linchuang Yixue
Subjects:
cholangiocarcinoma
zip4
glycolysis
kmt2e
mycn
Online Access:https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20250333
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https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20250333

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