Gegen-Sangshen oral liquid and its active fractions mitigate alcoholic liver disease in mice through repairing intestinal epithelial injury and regulating gut microbiota

Gegen-Sangshen oral liquid and its active fractions mitigate alcoholic liver disease in mice through repairing intestinal epithelial injury and regulating gut microbiota

Abstract Background Liuweizhiji Gegen-Sangshen oral liquid (LGS), as a Chinese medicinal preparation, is developed from a Traditional Chinese medicinal formula consisting of six Chinese medicinal herbs, including Puerariae lobatae radix, Hoveniae semen, Imperatae rhizoma, Crataegi fructus, Mori fruc...

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Main Authors: Shulin Wei, Mingxing Li, Long Zhao, Tiangang Wang, Ke Wu, Jiayue Yang, Yubin Liu, Yueshui Zhao, Fukuan Du, Yu Chen, Shuai Deng, Jing Shen, Zhangang Xiao, Wanping Li, Xiaobing Li, Yuhong Sun, Li Gu, Mei Wei, Zhi Li, Xu Wu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Chinese Medicine
Subjects:
Alcoholic liver disease
Gegen-Sangshen oral liquid
Gut-liver axis
Intestinal organoid
Gut microbiota
Online Access:https://doi.org/10.1186/s13020-024-01049-y
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https://doi.org/10.1186/s13020-024-01049-y

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