The effects of levetiracetam and a new 4-phenylpyrrolidone derivative GIZh-290 in a closed cross-maze in BALB/c and C57BL / 6 mice

The effects of levetiracetam and a new 4-phenylpyrrolidone derivative GIZh-290 in a closed cross-maze in BALB/c and C57BL / 6 mice

The study was aimed to compare the psychopharmacological effects of 2 anticonvulsant drugs levetiracetam ((S)-2-(2-oxopyrrolidin-1-yl) butanamide) and the new compound, GIZh-290 (2-oxo-4-phenylpyrrolidine-1-yl) acetic acid) on behavioral spectra of inbred mice BALB/c and C57BL/6 under conditions of...

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Bibliographic Details
Main Authors: I. G. Kovalev, E. V. Vasileva, R. O. Bokov, R. M. Salimov, G. I. Kovalev
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2017-03-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
противоэпилептический препарат
леветирацетам
соединение гиж-290
мыши balb/c и c57bl/6
ноотропное действие
тревожность
двигательная активность
закрытый крестообразный лабиринт
anticonvulsant
levetiracetam
4-phenylpyrrolidone derivative
mice
balb/c
c57bl/6
nootropic action
anxiety
motor activity
closed cross-maze test
Online Access:https://www.pharmacokinetica.ru/jour/article/view/15
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