Supramolecular nanofibers of natural asiaticoside for self-supporting gelation and enhanced transdermal delivery

Supramolecular nanofibers of natural asiaticoside for self-supporting gelation and enhanced transdermal delivery

ObjectivesThe study aimed to develop a supramolecular hydrogel of asiaticoside (AS) via self-assembly and evaluate its potential for enhanced transdermal delivery.Materials and MethodsAS was dissolved in dimethyl sulfoxide (DMSO) and dispersed into a glycerol–water mixture (3:7 v/v) via ultrasonicat...

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Bibliographic Details
Main Authors: Xixi Hu, Shuang Tian, Jiao Wang, Weixi Luo, Jiangli Yao, Rui Zhu, Yiyuan Dai, Hongyun Li, Yuhua Ma, Chen Liu, Wenping Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
asiaticoside
supramolecular hydrogel
self-assembled nanofibers
transdermal drug delivery
natural product gelator
molecular dynamics simulation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1589865/full
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https://www.frontiersin.org/articles/10.3389/fbioe.2025.1589865/full

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