Tertiary lymphoid structures potentially promote immune checkpoint inhibitor response in SMARCB1-deficient medullary renal cell carcinoma

Tertiary lymphoid structures potentially promote immune checkpoint inhibitor response in SMARCB1-deficient medullary renal cell carcinoma

Abstract The WHO’s classification of renal cell carcinoma (RCC) has identified loss of SMARCB1 as one of the driven mutations. Despite intensive postoperative interventions, the prognosis for SMARCB1-deficient medullary RCC remains poor, indicating insufficiency in current therapy. Herein, we report...

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Main Authors: Yanfeng Tang, Junru Chen, Mengxin Zhang, Xu Hu, Jingjing Guo, Yaowen Zhang, Yuntian Chen, Haoyang Liu, Junjie Zhao, Ni Chen, Guangxi Sun, Hao Zeng
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00756-x
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https://doi.org/10.1038/s41698-024-00756-x

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