Initiating Empagliflozin and Sacubitril/Valsartan Early After Acute Myocardial Infarction: Mechanistic Study

Initiating Empagliflozin and Sacubitril/Valsartan Early After Acute Myocardial Infarction: Mechanistic Study

Background Empagliflozin and sacubitril/valsartan are established in heart failure treatment, but their effects after myocardial infarction (MI) are less clear. This study evaluated early empagliflozin initiation, with or without sacubitril/valsartan, on post‐MI inflammation, oxidative stress, metab...

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Main Authors: Daina Martínez‐Falguera, Júlia Aranyó, Gemma Ferrer‐Curriu, Albert Teis, Elena Revuelta‐Lopez, Idoia Diaz‐Güemes, Marta Monguió‐Tortajada, Edgar Fadeuilhe, Oriol Rodríguez‐Leor, Francesc Poblador, Borja Montejo, Santiago Roura, Roger Villuendas, Axel Sarrias, Victor Bazan, Esther Jorge, Victoria Delgado, Francisco Rafael Jimenez‐Trinidad, Montserrat Rigol, Neus Martinez‐Micaelo, Núria Amigó, Antoni Bayes‐Genis, Felipe Bisbal, Carolina Gálvez‐Montón
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
empagliflozin
fibrosis
inflammation
myocardial infarction
sacubitril/valsartan
ventricular arrhythmia
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.040214
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https://www.ahajournals.org/doi/10.1161/JAHA.124.040214

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