Decreased number of myeloid-derived suppressor cells in the placental trophoblast of gestational diabetes mellitus. Possible role of leptin

Decreased number of myeloid-derived suppressor cells in the placental trophoblast of gestational diabetes mellitus. Possible role of leptin

Gestational diabetes mellitus (GDM) is the most common complication of pregnancy and significantly increases both maternal and fetal morbidity and mortality. Inflammation is a hallmark of GDM, and placental inflammation may play a key role in the pathophysiology of the disease. Myeloid-derived suppr...

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Main Authors: Malika Tami, Lourdes Hontecillas-Prieto, Daniel García-Domínguez, Rocío Flores-Campos, Teresa Vilariño-García, Flora Sánchez-Jiménez, Pilar Guadix, José L. Dueñas, Carlos Jiménez-Cortegana, Luis de la Cruz-Merino, Antonio Pérez-Pérez, Víctor Sánchez-Margalet
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Immunobiology
Subjects:
MDSC
Leptin
Placenta
Gestational diabetes mellitus
Online Access:http://www.sciencedirect.com/science/article/pii/S0171298525000312
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