The alteration of IL-17 signaling pathway in bipolar disorder: a preliminary study with transcriptomic perspective

The alteration of IL-17 signaling pathway in bipolar disorder: a preliminary study with transcriptomic perspective

ObjectiveBipolar Disorder (BD) is a complex psychiatric condition influenced by genetic and environmental factors. This study aims to explore global mRNA expression in Peripheral blood white cells (PBMC) of BD patients.MethodsWe analyzed whole-genome gene expression profiles from PBMC of 12 BD state...

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Main Authors: Xiaobo Wang, Su Yu, Zhen Gao, Fangming Xu, Yumei Wang, Tianle Zhang, Tingting Xie, Xihua Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Psychiatry
Subjects:
bipolar disorder
DEGs (differentially expressed genes)
IL-17 pathway
immunoinflammatory response
immune infiltration analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1539038/full
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https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1539038/full

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