Design and Synthesis of Hybrid Compounds for Potential Treatment of Bacterial Co-Infections: In Vitro Antibacterial and In Silico Studies

Design and Synthesis of Hybrid Compounds for Potential Treatment of Bacterial Co-Infections: In Vitro Antibacterial and In Silico Studies

<b>Background:</b> The need for innovative therapeutic strategies to enhance patient outcomes has increased due to the rise in bacterial co-infections associated with COVID-19. <b>Methods:</b> In this study, ten hybrid compounds were synthesized by combining two known pharmac...

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Bibliographic Details
Main Authors: Vuyolwethu Khwaza, Opeoluwa O. Oyedeji, Eric Morifi, Mutshinyalo Nwamadi, Thierry Youmbi Fonkui, Derek Tantoh Ndinteh, Blessing A. Aderibigbe
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Antibiotics
Subjects:
synthesis
hybrid compounds
antibacterial
in silico studies
SwissADME
COVID-19
Online Access:https://www.mdpi.com/2079-6382/14/6/582
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