Development and validation of a novel prognostic model to predict 1-year post-transplant mortality for acute-on-chronic hepatitis B liver failure: a nationwide, multicentre, cohort studyResearch in context

Development and validation of a novel prognostic model to predict 1-year post-transplant mortality for acute-on-chronic hepatitis B liver failure: a nationwide, multicentre, cohort studyResearch in context

Summary: Background: Liver transplantation (LT) provides a potential cure for hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF). We aimed to develop and externally validate a prognostic model to predict 1-year post-LT mortality in patients with HBV-ACLF. Methods: This retrospectiv...

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Main Authors: Li Zhuang, Yimou Lin, Yu Jia, Jun Fang, Yujian Zheng, Taishi Fang, Meiching Ong, Aibo Mu, Jiaxing Zhu, Mengchao Wang, Dong Zhao, Feiwen Deng, Qiucheng Lei, Leibo Xu, Zuozhong Yang, Qiang Sun, Wei Qu, Chenwei Xu, Zhijun Zhu, Chuanjiang Li, Hanyu Jiang, Jimin Liu, Xiaoshun He, Shusen Zheng, Zhiyong Guo, Qi Ling
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:EClinicalMedicine
Subjects:
Hepatitis B-Related acute-on-chronic liver failure
Liver transplantation
Post-transplant mortality
Prognostic model
Graft-recipient combination
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537025002974
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