T Cell Costimulatory Molecules in Anti-Viral Immunity: Potential Role in Immunotherapeutic Vaccines

T lymphocyte activation is required to eliminate or control intracellular viruses. The activation of T cells requires both an antigen specific signal, involving the recognition of a peptide/major histocompatibility protein complex by the T cell receptor, as well as additional costimulatory signals...

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Bibliographic Details
Main Authors: Tania H Watts, Edward M Bertram, Jacob Bukczynski, Tao Wen
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2003/214034
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