Ethanol extract of Garcinia kola seeds alleviates HGHFD/STZ-induced nonalcoholic fatty liver disease in diabetic rats by modulating oxidative stress, inflammation, and lipid accumulation

Ethanol extract of Garcinia kola seeds alleviates HGHFD/STZ-induced nonalcoholic fatty liver disease in diabetic rats by modulating oxidative stress, inflammation, and lipid accumulation

Objective(s): To investigate the ameliorative effects of Garcinia kola ethanol extract (EGK) on type 2 diabetes mellitus (T2DM) combined with nonalcoholic fatty liver disease (NAFLD) and to explore its underlying mechanisms. Materials and Methods: In vivo, a T2DM rat model was established using HGHF...

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Bibliographic Details
Main Authors: Xiaojing Sun, Yanxiang Yuan, Xianhao Xin, Ping Sun, Yunqi Sun, Mi Xie, Yuefei Wang, Shan Huang, Bin Li
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
garcinia kola
hepg2
lipid accumulation
srebp-1c
t2dm combined with - nafld
Online Access:https://ijbms.mums.ac.ir/article_25516_d22ffdd8a5ad82604fb19a3408cfae4d.pdf
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https://ijbms.mums.ac.ir/article_25516_d22ffdd8a5ad82604fb19a3408cfae4d.pdf

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