Optimization of SgRNA expression with RNA pol III regulatory elements in Anopheles stephensi

Optimization of SgRNA expression with RNA pol III regulatory elements in Anopheles stephensi

Abstract Anopheles stephensi, a major Asian malaria vector, is invading Africa and has been implicated in recent outbreaks of urban malaria. Control of this species is key to eliminating malaria in Africa. Genetic control strategies, and CRISPR/Cas9-based gene drives are emerging as promising specie...

Full description

Saved in:
Bibliographic Details
Main Authors: Estela Gonzalez, Michelle A. E. Anderson, Joshua X. D. Ang, Katherine Nevard, Lewis Shackleford, Mireia Larrosa-Godall, Philip T. Leftwich, Luke Alphey
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
CRISPR/Cas9
Gene drive
Mosquito
Malaria
Online Access:https://doi.org/10.1038/s41598-025-98557-0
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-98557-0

Similar Items