Characterization of extracellular vesicle-associated DNA and proteins derived from organotropic metastatic breast cancer cells

Characterization of extracellular vesicle-associated DNA and proteins derived from organotropic metastatic breast cancer cells

Abstract Background While primary breast cancer (BC) is often effectively managed, metastasis remains the primary cause of BC-related fatalities. Gaps remain in our understanding of the mechanisms regulating cancer cell organotropism with predilection to specific organs. Unraveling mediators of site...

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Bibliographic Details
Main Authors: Amélie Nadeau, Thupten Tsering, Mohamed Abdouh, Laura Kienzle, Jenna Cleyle, Lorne Taylor, Noélie Douanne, Kyle Dickinson, Peter M. Siegel, Julia V. Burnier
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Extracellular vesicles
Metastatic breast cancer
Organotropism
Proteomics
DNA
Biomarkers
Online Access:https://doi.org/10.1186/s13046-025-03418-3
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https://doi.org/10.1186/s13046-025-03418-3

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