The known unknowns of the Hsp90 chaperone

The known unknowns of the Hsp90 chaperone

Molecular chaperones are vital proteins that maintain protein homeostasis by assisting in protein folding, activation, degradation, and stress protection. Among them, heat-shock protein 90 (Hsp90) stands out as an essential proteostasis hub in eukaryotes, chaperoning hundreds of ‘clients’ (substrate...

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Bibliographic Details
Main Authors: Laura-Marie Silbermann, Benjamin Vermeer, Sonja Schmid, Katarzyna Tych
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
Hsp90
molecular chaperones
proteostasis
Online Access:https://elifesciences.org/articles/102666
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