Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells.

Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells.

<h4>Objective</h4>Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, with high mortality rates partially due to limited therapeutic options and drug resistance. Arsenic trioxide (ATO), a compound clinically proven for acute promyelocytic leukemia (APL),...

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Bibliographic Details
Main Authors:	Mi Huang, Duanzhuo Li, Zhengzhen Xia, Shengjie Liao, Wenxia Si, Chao Yuan, Yanli Liao, Weibin Wu, Minshu Jiang, Xin Yu, Yi Quan
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0322746
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