Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells.

<h4>Objective</h4>Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, with high mortality rates partially due to limited therapeutic options and drug resistance. Arsenic trioxide (ATO), a compound clinically proven for acute promyelocytic leukemia (APL),...

Full description

Saved in:
Bibliographic Details
Main Authors: Mi Huang, Duanzhuo Li, Zhengzhen Xia, Shengjie Liao, Wenxia Si, Chao Yuan, Yanli Liao, Weibin Wu, Minshu Jiang, Xin Yu, Yi Quan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0322746
Tags: Add Tag
No Tags, Be the first to tag this record!