Dynamic phosphorylation of Fascin-1 orchestrates microglial phagocytosis and neurological recovery after spinal cord injury

Abstract The persistence of myelin debris after spinal cord injury (SCI) constitutes a formidable barrier to axonal regeneration, remyelination, and functional recovery by initiating inflammatory cascades. Microglia, known for their superior phagocytic and degradative capabilities, are crucial in cl...

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Bibliographic Details
Main Authors: Yanchang Liu, Fei Yao, Ziyu Li, Yan Jiang, Jianjian Li, Shuisheng Yu, Xuyang Hu, Fangru Ouyang, Meige Zheng, Li Cheng, Juehua Jing
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-025-03445-z
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