Research progress on PIEZO1 protein structure and activation mechanism by small-molecule agonists
Piezo1, a non-selective cation channel, can transduce diverse mechanical stimuli into electrochemical signals and perform essential physiological functions in the human body. Anomalous Piezo1 activities due to loss-of-function mutations are linked to diverse pathological states ranging from anemia,...
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| Main Authors: | Danjiang Li, Yuanyuan Song, Yuan Zeng, Hua Hu, Wei Tian |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-03-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625000414 |
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