Research progress on PIEZO1 protein structure and activation mechanism by small-molecule agonists

Piezo1, a non-selective cation channel, can transduce diverse mechanical stimuli into electrochemical signals and perform essential physiological functions in the human body. Anomalous Piezo1 activities due to loss-of-function mutations are linked to diverse pathological states ranging from anemia,...

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Bibliographic Details
Main Authors: Danjiang Li, Yuanyuan Song, Yuan Zeng, Hua Hu, Wei Tian
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Results in Chemistry
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625000414
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