Predicting progression of Alzheimer's disease using ordinal regression.

Predicting progression of Alzheimer's disease using ordinal regression.

We propose a novel approach to predicting disease progression in Alzheimer's disease (AD)--multivariate ordinal regression--which inherently models the ordered nature of brain atrophy spanning normal aging (CTL) to mild cognitive impairment (MCI) to AD. Ordinal regression provides probabilistic...

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Main Authors: Orla M Doyle, Eric Westman, Andre F Marquand, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kłoszewska, Hilkka Soininen, Simon Lovestone, Steve C R Williams, Andrew Simmons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0105542
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https://doi.org/10.1371/journal.pone.0105542

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