Gene expression profiling and pathway analysis in head and neck squamous cell carcinoma: focus on disulfidptosis

Gene expression profiling and pathway analysis in head and neck squamous cell carcinoma: focus on disulfidptosis

Abstract This study aimed to characterize the prognostic and therapeutic implications of disulfidptosis-related genes (DRGs) in head and neck squamous cell carcinoma (HNSCC). Using multi-omics data from the Cancer Genome Atlas (TCGA) (n = 500) and Gene Expression Omnibus (GEO) cohorts (n = 270), we...

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Bibliographic Details
Main Authors: Yajun Tong, Site Bai, Ludi Ou, Qiang Zhou, Songlian Liu, Leilan Yin, Kewei Tang, Ling Long, Qinghua Yin
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
Subjects:
Head and neck squamous cell carcinoma (HNSCC)
Disulfidptosis-related genes (DRGs)
Prognostic model
Immunotherapy response
Drug sensitivity
Online Access:https://doi.org/10.1007/s12672-025-02344-2
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https://doi.org/10.1007/s12672-025-02344-2

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