Serum cystatin C as a potential biomarker for generalized acetylcholine receptor antibody-positive myasthenia gravis

Serum cystatin C as a potential biomarker for generalized acetylcholine receptor antibody-positive myasthenia gravis

ObjectiveTo identify new metabolic biomarkers associated with myasthenia gravis (MG).MethodsWe analyzed 285 potential metabolic molecules from UK Biobank (UKB) for MG patients and identified elevated serum cystatin C (Cys-C). Validation was performed using laboratory data, ELISA, and clinical inform...

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Main Authors: Dingxian He, Huahua Zhong, Lei Jin, Ran Chen, Zongtai Wu, Rui Zhao, Xiao Huan, Chong Yan, Jie Song, Jianying Xi, Chongbo Zhao, Shanfeng Zhu, Sushan Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
myasthenia gravis
cystatin C
biomarker
T helper cell
clinical severity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578359/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578359/full

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