Cancer cachexia and weight loss before CAR T-cell therapy for lymphoma are independently associated with poor outcomes

Cancer cachexia and weight loss before CAR T-cell therapy for lymphoma are independently associated with poor outcomes

Abstract: Chimeric antigen receptor (CAR) T-cell therapy has transformed the care of lymphoma, yet many patients relapse. Several prognostic markers have been associated with CAR T-cell outcomes, such as tumor burden, response to bridging chemotherapy, and laboratory parameters at the time of lympho...

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Main Authors: Yannis K. Valtis, Sean Devlin, Roni Shouval, Kai Rejeski, Magdalena Corona, Alejandro Luna De Abia, Alfredo Rivas-Delgado, Efrat Luttwak, Giulio Cassanello, Ivan Landego, Heiko Schöder, Akshay Bedmutha, Alexander Boardman, Gunjan L. Shah, Michael Scordo, Miguel-Angel Perales, Gilles Salles, M. Lia Palomba, Urvi A. Shah, Jae H. Park
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952924006359
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http://www.sciencedirect.com/science/article/pii/S2473952924006359

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