Naphthenic Acid Fraction Components-Induced Metabolic and Mitochondrial Alterations in Rat Hepatoma Cells: Monitoring Metabolic Reprogramming with Tryptophan–Kynurenine Ratio

Naphthenic Acid Fraction Components-Induced Metabolic and Mitochondrial Alterations in Rat Hepatoma Cells: Monitoring Metabolic Reprogramming with Tryptophan–Kynurenine Ratio

Altered body condition and diminished growth in wildlife in the Alberta Oil Sands Region (AOSR) are prompting investigations into the impact of oil sands industrial activity on wildlife in the region. Chemical constituents from bitumen-influenced waters, including oil sands process-affected water (O...

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Bibliographic Details
Main Authors: Laiba Jamshed, Amica Marie-Lucas, Genevieve A. Perono, Gregg T. Tomy, Jim J. Petrik, Richard A. Frank, L. Mark Hewitt, Philippe J. Thomas, Alison C. Holloway
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Journal of Xenobiotics
Subjects:
AOSR
NAFC
mitochondrial dysfunction
metabolic reprogramming
metabolic switch
substrate utilization
Online Access:https://www.mdpi.com/2039-4713/15/3/61
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